About the Mid-South CDRN

What is the Mid-South CDRN?

The Mid-South Clinical Data Research Network (CDRN) was founded in 2014 under PCORI Phase I funding. It was one of 11 such awards announced by the Patient-Centered Outcomes Research Institute (PCORI), an independent, non-profit organization authorized by Congress in 2010 to fund research aimed at improving the health of entire populations.

In Phase I, the Mid-South CDRN developed significant infrastructure, including:

  1.  CDRN organizational structure and policies;
  2. the PCORnet common data model (CDM);
  3. informatics tools for electronic patient identification, contact, consent, surveying, and payment;
  4. stakeholder engagement infrastructure, and surveying of over 1,200 patients and clinicians;
  5. regulatory processes; and
  6. operational processes for assessing and acting on requests for CDRN resources.

Additionally, we successfully recruited patients, including the surveying of over 6,000 patients for our weight, coronary heart disease, and sickle cell disease cohorts.

Conducting research is the main focus of Phase II. We offer a wide array of research activities including pre-research and complex queries, observation research, interventional studies, and pragmatic research. Our CDRN has already collaborated on the planning and conduct of many research projects including projects with CDRNs, PPRNs, academic institutions, and the health industry. We are also actively participating in the PCORI-funded pragmatic trial on aspirin dosing and the planned PCORI observational studies on obesity.


If you have any questions feel free to contact us via email at midsouthcdrn@vanderbilt.edu.